β受体阻滞剂

β受体阻断药
Beta blockers
β受体阻断药; Beta blockers
药物种类
	普萘洛尔的键线式结构，是第一种成功应用于临床的β受体阻断药
用途	高血压、心律不齐等
生物靶标	β受体
ATC代码	C07
外部链接
MeSH	D000319
AHFS/Drugs.com	药物分类
消费者报告	Best Buy Drugs
WebMD	medicinenet rxlist

β受体阻断药（法語：Bêta-bloquants；英語：Beta blockers），又称Beta受体阻断药、β受体阻断剂、β受体阻滞剂、β受体拮抗剂或β阻断药，是一类用来治疗心律不齐、防止心脏病发作后的二次心脏病发作（二级预防）和在某些情况下用来治疗高血压的药物。^[1]^[2]^[3]

β受体阻断药非竞争性阻断交感神经系统中内源性儿茶酚胺肾上腺素和去甲肾上腺素的作用，尤其是肾上腺素能β受体。^[4]^[5]有些药物阻断所有β-肾上腺素能受体，有些则为竞争性阻断。

例子

二氯異丙腎上腺素（英语：Dichloroisoprenaline），第一种β受体阻断药

普萘洛尔（Propranolol）
毕索洛尔（Bisoprolol）

引用

^ Freemantle N, Cleland J, Young P, Mason J, Harrison J. beta Blockade after myocardial infarction: systematic review and meta regression analysis. BMJ. June 1999, 318 (7200): 1730–7. PMC 31101 . PMID 10381708. doi:10.1136/bmj.318.7200.1730.
^ Cruickshank JM. Beta blockers in hypertension. Lancet. August 2010, 376 (9739): 415; author reply 415–6. PMID 20692524. doi:10.1016/S0140-6736(10)61217-2.
^ Kaplan, Norman M. Choice of therapy in primary (essential) hypertension: Clinical trials. UpToDate. October 2010.
^ Frishman W.H.; Cheng-Lai A; Nawarskas J. Current Cardiovascular Drugs. Current Science Group. 2005: 152 [2010-09-07]. ISBN 978-1-57340-221-7.
^ Arcangelo V.P.; Peterson A.M. Pharmacotherapeutics for advanced practice: a practical approach. Lippincott Williams & Wilkins. 2006: 205 [2010-09-07]. ISBN 978-0-7817-5784-3.

[pmid10381708-1] Freemantle N, Cleland J, Young P, Mason J, Harrison J. beta Blockade after myocardial infarction: systematic review and meta regression analysis. BMJ. June 1999, 318 (7200): 1730–7. PMC 31101 . PMID 10381708. doi:10.1136/bmj.318.7200.1730.

[pmid20692524-2] Cruickshank JM. Beta blockers in hypertension. Lancet. August 2010, 376 (9739): 415; author reply 415–6. PMID 20692524. doi:10.1016/S0140-6736(10)61217-2.

[UpToDateHypertension-3] Kaplan, Norman M. Choice of therapy in primary (essential) hypertension: Clinical trials. UpToDate. October 2010.

[urlCurrent_Cardiovascular_Drugs_-_Google_Books-4] Frishman W.H.; Cheng-Lai A; Nawarskas J. Current Cardiovascular Drugs. Current Science Group. 2005: 152 [2010-09-07]. ISBN 978-1-57340-221-7.

[urlPharmacotherapeutics_for_advanced_..._-_Google_Books-5] Arcangelo V.P.; Peterson A.M. Pharmacotherapeutics for advanced practice: a practical approach. Lippincott Williams & Wilkins. 2006: 205 [2010-09-07]. ISBN 978-0-7817-5784-3.

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