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N95 respirator

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(Redirected from Surgical N95)
"N95" redirects here. For other uses, see N95 (disambiguation).
Further information: NIOSH air filtration rating

N95 respirator
Moldex 1512 N95
Other name(s)N95, N95 mask
Regulated byNational Institute for Occupational Safety and Health, Food and Drug Administration
Regulation42 CFR 84, 21 CFR 878.4040
NIOSH scheduleTC-84A

An N95 respirator is a disposable filtering facepiece respirator or reusable elastomeric respirator filter that meets the U.S. National Institute for Occupational Safety and Health (NIOSH) N95 standard of air filtration, filtering at least 95% of airborne particles that have a mass median aerodynamic diameter of 0.3 micrometers under 42 CFR 84, effective July 10, 1995. A surgical N95 is also rated against fluids, and is regulated by the US Food and Drug Administration under 21 CFR 878.4040, in addition to NIOSH 42 CFR 84. 42 CFR 84, the federal standard which the N95 is part of, was created to address shortcomings in the prior United States Bureau of Mines respirator testing standards, as well as tuberculosis outbreaks, caused by the HIV/AIDS epidemic in the United States. Since then, N95 respirator has continued to be used as a source control measure in various pandemics that have been experienced in the United States and Canada, including the 2009 swine flu and the COVID-19 pandemic.

The N95 respirator is commonly made of a fine mesh of synthetic polymer fibers, specifically a nonwoven polypropylene fabric.[1] It is produced by melt blowing and forms the inner filtration layer that filters out hazardous particles.[2] However, the N95 standard does not preclude alternative means of filtration,[3] so long as the respirator meets N95 standards and is approved by NIOSH.

The N95 is a trademark of the United States Department of Health and Human Services. It is illegal in the United States to use the term "N95" without the approval of NIOSH.

Regulation

[edit]

The N95 standard does not require that the respirator be resistant to oil; two other standards, R95 and P95, add that requirement.[4] The N95 type is the most common filtering facepiece respirator.[5] Current filters are an example of a mechanical filter respirator, which provides protection against particulates but not against gases or vapors.[6] An authentic N95 respirator is marked with the text "NIOSH" or the NIOSH logo, the filter class ("N95"), and, for most filtering facepiece respirators (respirators with non-replaceable filters), a "TC" approval number of the form 84A-####, the approval number. All N95 respirators, regardless of type, must be listed on the NIOSH Certified Equipment List (CEL)[7] or the NIOSH Trusted-Source page,[8] and it must have headbands instead of ear loops.[9]

N95 respirators are considered similar to other respirators regulated under non-U.S. jurisdictions, but slightly different criteria are used to certify their performance, such as the filter efficiency, test agent and flow rate, and permissible pressure drop. For example, FFP2 respirators of the European Union are required to meet at least 94% filtration, and KN95 respirators of China are expected to meet at least 95% filtration.[10] However, NIOSH found that some products labeled "KN95" failed to meet these standards, some of them filtering out as little as one percent.[11] Both the U.S. Food and Drug Administration and Health Canada require such KN95 products failing to meet the filtration standards to be re-labeled as "face masks" instead of "respirators",[12][13] when being sold in the U.S. and Canada.

Examples of N95 respirators
  • A Moldex N95 respirator
    A Moldex 2200N95 disposable filtering facepiece respirator, with TC approval number on the strap, TC-84A-0327
  • A 3M 1860 filtering facepiece respirator with fluid resistance
    Surgical N95 respirators for use in health care are both approved by NIOSH (as a respirator) and cleared by FDA (as a fluid resistant surgical mask), TC-84A-0006
  • Moldex Elastomeric Respirator with N95 filter circled
    An elastomeric respirator with N95 filters installed. Note the lack of a TC number; according to OSHA, TC numbers may be located in the respirator manual or on respirator packaging.[14]
Thoroughly check the NIOSH Certified Equipment List, and compare the look and feel to known good respirators
to verify that a suspect respirator is a NIOSH-approved N95.[15]

History

[edit]
For a broader, non-regulatory historical overview, see Respirator § History.

Early US respirator standards

[edit]
Hawks Nest Tunnel Disaster memorial signage
A memorial for the workers of the Hawks Nest Tunnel who died of silicosis

Prior to the 1970s, respirator standards were under the purview of the US Bureau of Mines (USBM). An example of an early respirator standard, Type A, established in 1926, was intended to protect against mechanically generated dusts produced in mines. These standards were intended to obviate miner deaths, noted to have reached 3,243 by 1907. However, prior to the Hawks Nest Tunnel Disaster, these standards were merely advisory, as the USBM had no enforcement power at the time.[16] After the disaster, an explicit approval program was established in 1934, along with the introduction of combination Type A/B/C respirator ratings, corresponding to Dusts/Fumes/Mists respectively, with Type D blocking all three, under 30 CFR 14 Schedule 21.[17]

The Federal Coal Mine Health and Safety Act establishing MESA (later MSHA),[18] the Occupational Safety and Health Act of 1970, establishing NIOSH,[19] as well as other regulations established around the time, reshuffled regulatory authority for respirators, and moved regulations from Part 14 to Part 11 by 1972,[4] but nonetheless continued the use of USBM-era regulations.[17]

42 CFR 84

[edit]
This article is about the Part 84 respirator regulation enacted in 1995. Not to be confused with the older, 1973 Part 84 regulation for colorimetric detector tubes,[20] which will not be discussed here.
NIOSH Recommended Guidelines for Personal Respiratory Protection scan
Respirator guidelines for TB were created by NIOSH as a result of the HIV/AIDS-induced outbreak in US hospitals
(Read on Wikisource)
This article is part of a series on
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Image on left: User seal check
An image of a the cover of the United States CFR. For Part 84, go to page 501.
N95 standard development is documented in the Federal Register, and the Code of Federal Regulations

Historically, respirators in the US had generally been approved by MESA/MSHA/NIOSH under federal regulation 30 CFR 11.[21] Plans for overhauling Part 11 regulations had been discussed since the late 1980s,[22] with the first proposed rule being published in the Federal Register on August 27, 1987. From the start, respirator regulations were planned to be moved from Title 30 to Title 42, Part 84 in the Code of Federal Regulations, along with the elimination of joint-approval between NIOSH and MSHA. Respirator assigned protection factors were also to be updated, along with chemical cartridge requirements.[23][24]

TB outbreak during the HIV epidemic

[edit]

In 1992, the multidrug-resistant tuberculosis task force within the CDC was tasked with reducing the incidences of hospital acquired TB infections. TB infections had traditionally occurred mainly in underserved groups and areas, as well as the very young and elderly, but regardless, usually had around a 10% chance of turning into an active TB infection in a given person's lifetime. However, HIV/AIDS, (where the outbreak in the US was in full force at the time) was noted to be one of the strongest factors for TB activation, since most TB outbreaks and mortalities reported at the time involved healthcare workers and patients infected with HIV. Respiratory protection and the performance of respirators were emphasized in the 1994 guidelines to controlling TB, which, at the time, were limited to respirators equipped with HEPA filters.[a][25]

To quickly address the HEPA-only[a] respirator requirement for TB controls, stemming from the lack of biological protection in the existing 30 CFR 11 standards (which were mainly designed for miners), NIOSH aimed to have the proposed 42 CFR rule changes finished by the end of 1994. The proposal at the time would drop the HEPA classification for non-powered respirators, and add three respirator types, at the time called Type A, B and C, with filtration efficiencies of greater than or equal to 99.97%, 99%, and 95% respectively,[22] with Type C corresponding to the current N95 standard.

According to NIOSH, all the new respirator types proposed in 42 CFR 84, including Type C (later N95), would meet the CDC's requirement for protection against TB, and would provide avenues for cheaper NIOSH-approved respirators without the need for HEPA[a] or NIOSH class-100 filters.[22]

After the passage of 42 CFR 84, a 1999 NIOSH guide for health care administrators noted that respirators selected for TB prevention under 42 CFR would likely be N95 respirators.[26]

Approval of Part 84 and replacement of 30 CFR 11

[edit]

On July 10, 1995, in response to respirators exhibiting "low initial efficiency levels", new 42 CFR 84 standards, including the N95 standard, were enforced under a three-year transition period,[27] ending on July 10, 1998.[4] The standard for N95 respirators includes, but is not limited to, a filtration of at least 95% under a 0.3 micrometer[28] 200 milligram test load of sodium chloride. Standards and specifications are also subject to change.[29][4]

Once 42 CFR 84 was in effect, MSHA, under a proposed rule change to 30 CFR 11, 70, and 71, would withdraw from the approval process of rated respirators (outside of respirators used for mining).[22][30]

Use

[edit]

When mandated by United States employers

[edit]
CDC/NIOSH infographic
Infographic on three key factors required for a respirator to be effective
CDC/NIOSH beard guide
For men, certain beards can worsen fit.
CDC/NIOSH document for user seal check
Guidance for performing a user seal check, which is required every time a respirator is put on

Fit testing is a critical component to a respiratory protection program whenever workers use tight-fitting respirators. OSHA (US) requires an initial respirator fit test to identify the right model, style, and size respirator for each worker; as well, as annual fit tests. Additionally, tight-fitting respirators, including the N95, require a user seal check each time one is put on. Facial hair at the sealing area of the respirator will cause it to leak.[31]

Before use of a respirator can be mandated by an employer, OSHA regulations require a medical evaluation.[32] In the United States medical evaluation is required once, prior to initial fit testing and use, although it may need to be repeated if any adverse signs or symptoms are observed.[33] Correct use of the respirator decreases the chances of airborne contamination by viruses.[34]

For persons who are medically disqualified from negative-pressure respirators, or who cannot pass a fit test due to facial hair or other reasons, a powered air-purifying respirator is a possible alternative.[35][36]

In industry

[edit]

N95 respirators are also designed for industrial use in sectors such as mining and construction.[37] They have also been shown to be effective as protection against engineered nanoparticles.[38]: 12–14 [39][40]

According to the NIOSH Respirator Selection Logic, respirators with filters in the N, R, and P series are recommended for concentrations of hazardous particulates that are greater than the relevant occupational exposure limit but less than the immediately dangerous to life or health level and the manufacturer's maximum use concentration, subject to the respirator having a sufficient assigned protection factor.[41][42]

N series respirators, including the N95 respirator, are only effective in the absence of oil particles, such as lubricants, cutting fluids, or glycerine. For substances hazardous to the eyes, a respirator equipped with a full facepiece, helmet, or hood is recommended. They are not effective during firefighting, in oxygen-deficient atmosphere, or in an unknown atmosphere; in these situations a self-contained breathing apparatus is recommended instead. They are not effective against hazardous gases or vapors, for which a cartridge respirator is recommended.[42]

In industrial settings where infectious disease exposure is not a concern, users can wear and reuse a filtering facepiece respirator until it is damaged, soiled, or causing noticeably increased breathing resistance, unless there is a manufacturer-specified duration of use. However, in laboratories at biosafety level 2 and higher, respirators are recommended to be discarded as hazardous waste after a single use.[43]

Some industrial N95 series respirators have an exhaust valve to improve comfort, making exhalation easier, reducing leakage on exhalation and steaming-up of glasses. Research has indicated that wearing a valved N95 respirator does provide some source control to prevent the spread of diseases like COVID-19 when worn by asymptomatic infected users, at a level similar to that of a surgical or cloth facemask, although it is not equivalent to the performance of unvalved respirators.[44] The same study found that "[m]odifications [such as the use of an electrocardiogram pad or surgical tape secured over the valve from the inside of the FFR] [...] can further reduce particle emissions".[44]

In healthcare

[edit]
Person wearing a surgical N95 respirator
A U.S. Navy sailor wearing a surgical N95 respirator

Respirators used in healthcare are traditionally a specific variant called a surgical respirator, which is both approved by NIOSH as a respirator and cleared by the Food and Drug Administration as a medical device similar to a surgical mask.[45] These may also be labeled "Surgical N95", "medical respirators", or "healthcare respirators".[46] The difference lies in the extra fluid-resistant layer outside, typically colored blue.[47] In addition to 42 CFR 84, surgical N95s are regulated under FDA regulation 21 CFR 878.4040.[37]

In the United States, the Occupational Safety and Health Administration (OSHA) requires healthcare workers who are expected to perform patient activities with those suspected or confirmed to be infected with COVID-19 to wear respiratory protection, such as an N95 respirator.[31] The CDC recommends the use of respirators with at least N95 certification to protect the wearer from inhalation of infectious particles including Mycobacterium tuberculosis, avian influenza, severe acute respiratory syndrome (SARS), pandemic influenza, and Ebola.[48]

Unlike a respirator, a surgical mask is designed to provide barrier protection against droplets and does not have an air-tight seal and thus does not protect its wearer against airborne particles such as virus material to the same extent.[31]

Use during shortages

[edit]
Further information: COVID-19 pandemic § Face masks and respiratory hygiene

During crisis situations where there is a shortage of N95 respirators, such as the COVID-19 pandemic, the U.S. Centers for Disease Control and Prevention (CDC) has recommended strategies for optimizing their use in healthcare settings.[49] N95 respirators can be used beyond their manufacturer-designated shelf life, although components such as the straps and nose bridge material may degrade, making it particularly important that the wearer perform the expected seal check.[49][50] N95 respirators can be reused a limited number of times after being removed, as long as they have not been used during aerosol-generating procedures and are not contaminated with patients' bodily fluids, because this increases the risk of surface contamination with pathogens. The respirator manufacturer may recommend a maximum number of donnings or uses; if no manufacturer guidance is available, preliminary data suggests limiting to five uses per device.[49][51] Respirators approved under standards used in other countries and are similar to NIOSH-approved N95 respirators—including FFP2 and FFP3 respirators regulated by the European Union—can be used.[49]

According to NIOSH, respirators may still be used in crisis situations if standard respirator fit testing is not available, as a respirator will still provide better protection than a surgical mask or no mask. In this case, best practices for getting a good face seal include trying different models or sizes, using a mirror or asking a colleague to check that the respirator is touching the face, and doing multiple user seal checks.[31]

Given that the global supply of personal protective equipment (PPE) may be insufficient during a pandemic, in 2020, the World Health Organization recommended minimizing the need for PPE through telemedicine; physical barriers such as clear windows; allowing only those involved in direct care to enter a room with a COVID-19 patient; using only the PPE necessary for the specific task; continuing use of the same respirator without removing it while caring for multiple patients with the same diagnosis; monitoring and coordinating the PPE supply chain; and discouraging the use of masks for asymptomatic individuals.[52]

When it is no longer possible for all healthcare workers to wear N95 respirators when caring for a COVID-19 patient, the CDC recommends that respirators be prioritized for workers performing aerosol-generating procedures on symptomatic persons, and those within three feet of an unmasked symptomatic person. Under these conditions, masking of symptomatic patients with at least a surgical mask and maintaining distance from the patient are particularly important to reduce the risk of transmission. When no respirators are left, workers who are at higher risk for severe illness may be excluded from caring for patients, and workers who have clinically recovered from COVID-19 may be preferred to care for patients. Portable fans with HEPA filters may also be used to increase ventilation in isolation rooms when surgical masks are being used in place of respirators. If neither respirators nor surgical masks are available, as a last resort, it may be necessary for healthcare workers to use masks that have never been evaluated or approved by NIOSH or homemade masks, such as cloth face masks, although caution should be exercised when considering this option.[49]

Decontamination

[edit]

Disposable filtering facepiece respirators such as N95 respirators are not approved for routine decontamination and reuse as standard of care. However, their decontamination and reuse may need to be considered as a crisis capacity strategy to ensure continued availability.[53][54]

There have been efforts to evaluate cleaning methods for respirators in emergency shortages, although there is concern that this may reduce filter performance, or affect mask fit by deforming the mask.[55][56][57] Duke University researchers have published a method for cleaning N95 respirators without damaging them using vaporized hydrogen peroxide to allow reuse for a limited number of times.[58][59][60] Battelle received an Emergency Use Authorization from the U.S. Food and Drug Administration for its technology used to sterilize N95 respirators.[61]

OSHA does not currently have any standards for disinfecting N95 respirators.[56] NIOSH recommends that during shortages N95 respirators may be used up to five times without cleaning them, as long as aerosol-generating procedures are not performed, and respirators are not contaminated with patients' bodily fluids. Contamination can be reduced by wearing a cleanable face shield over an N95 respirator, as well as using clean gloves when donning and seal-checking a used N95 respirator and discarding the gloves immediately after.[51] According to CDC, ultraviolet germicidal irradiation, vaporous hydrogen peroxide and moist heat showed the most promise as potential methods to decontaminate N95 respirators and other filtering facepiece respirators.[53]

Contrast with surgical mask

[edit]
A table listing the attributes of surgical masks and N95 respirators in eight categories
An infographic on the difference between surgical masks and N95 respirators

A surgical mask is a loosely-placed, unsealed barrier, meant to stop droplets, and other liquid-borne particles from the mouth and nose that may contain pathogens.[62]

A surgical mask may not block all particles, due to the lack of fit between the surface of the face mask and the face.[62] The filtration efficiency of a surgical mask ranges between 10% and 90% for any given manufacturer, when measured using tests required for NIOSH certification. A study found that 80–100% of subjects failed an OSHA-accepted qualitative fit test, and a quantitative test showed between 12 and 25% leakage.[63]

A CDC study found that in public indoor settings, consistently wearing a respirator was linked to a 83% lower risk of testing positive for COVID-19, as compared to a 66% reduction when using surgical masks, and 56% for cloth.[64]

History during pandemics

[edit]

HIV/AIDS and TB epidemic

[edit]
See also: HIV/AIDS in the United States and Source control (respiratory disease) § US HIV/AIDS Epidemic
A STOP sign
Under a rule proposed by OSHA, this sign would be paired with the words No Admittance Without Wearing a Type N95 or More Protective Respirator near where TB is present[65]

While NIOSH was busy finishing 42 CFR 84 respirator regulations (including the N95), other agencies and groups (such as the SEIU[66]) were advocating for new standards for the prevention of TB. In 1992, the Labor Coalition to Fight TB in the Workplace started lobbying OSHA to create advisories and formal rules to protect workers from TB. The group was especially concerned about the rise of multidrug-resistant tuberculosis, which would require more rigorous standards to mitigate, especially since they felt that the 1990 CDC guidelines for TB were not being properly followed. The CDC eventually revised and released new TB guidelines in 1994, and in 1995 and 1996, meetings started to be held between OSHA and various stakeholders for a new TB standard, borrowing heavily from the CDC's work.[67][65]

In 1997, OSHA proposed new rule changes for industries affected by the spread of tuberculosis, like hospitals, where many patients infected with TB were also infected with HIV. The proposed rule would require signage that includes a STOP sign, with red background, white symbols, and a set of words warning people to wear "N95 or more protective" respirators (under 42 CFR 84) near isolation rooms where TB infection is likely. Additional notices could be added at the discretion of an employer, so long as it did not contradict the required wording.[65]

OSHA withdrew the proposal in 2003, owing to commenters and reviewers pointing to a likely overstating of risk, declining rates of TB in the years following the proposal, as well as compliance without a rule by OSHA.[68]

SARS pandemic

[edit]
See also: 2002–2004 SARS outbreak
Lab worker with mask
A lab worker wearing an N95 respirator during the SARS outbreak

In 2003, in response to the SARS outbreak, the United States CDC advised healthcare workers to wear N95 respirators.[69] Despite this advice, a patient who had traveled from Ontario exposed six healthcare workers in Pennsylvania following contact tracing by the CDC, though fitted N95 respirators were worn at a hospital upon suspicion of SARS.[70]

Following the SARS outbreak in the US, US Senate hearings started to be held proposing the Strategic National Stockpile start stocking PPE and N95 respirators in the event of another SARS outbreak. It was noted at the time that there were few N95 respirator manufacturers, potentially exacerbating a shortage in a crisis.[71]

Meanwhile, in Canada, discussions with Ontario EMS and New York Department of Health in 2004 noted that infected emergency medical personnel failed to properly use N95 respirators.[72] According to Ontario SARS commission final report, this was likely due to confusion over infectious disease control, confusion over respirator procedures, and the insinuation by various infection control practitioners that N95 respirators were not necessary. However, the report concludes, from laws preceding SARS, healthcare workers were obligated to wear N95 respirators throughout the outbreak, despite suggestions to the contrary.[73] A paper published in the New England Journal of Medicine concluded that universal use of N95 respirators, as well as additional infection control measures, ended the SARS outbreak in Ontario.[74]

2007 CDC/HICPAC infection control guidelines

[edit]
These paragraphs are an excerpt from Source control (respiratory disease) § Pre-COVID.[edit]

In 2007, the CDC HICPAC published a set of guidelines, called the 2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings, suggesting that use of "barrier precautions", defined as "masks, gowns, [and] gloves", would not be required, so long as it was limited to "routine entry", patients were not confirmed to be infected, and no aerosol-generating procedures were being done. "Standard precautions" requiring the use of masks, face shields, and/or eye protection, would be needed if there was potential for the spraying of bodily fluids, like during intubation.[75][76]

The guidelines are the same regardless of the type of pathogen, but the guidelines also note that, based on the experience of SARS-CoV in Toronto, that "N95 or higher respirators may offer additional protection to those exposed to aerosol-generating procedures and high risk activities".[75]

Separate from "barrier precautions" and "standard precautions" are "airborne precautions", a protocol for "infectious agents transmitted by the airborne route", like with SARS-CoV and tuberculosis, requiring 12 air changes per hour for new facilities, and use of fitted N95 respirators. These measures are used whenever someone is suspected of harboring an "infectious agent".[75][76]

H1N1 swine flu pandemic

[edit]
See also: 2009 swine flu pandemic

In May 2009, in response to the H1N1 swine flu outbreak, the CDC authorized the release of N95 respirators from the Strategic National Stockpile, and the waiving of certain quality controls on certain models of newly manufactured N95 respirators, provided they were documented "for use during the swine flu emergency".[77] Initially, the CDC's interim guide for H1N1 recommended N95 respirators for the prevention of H1N1, but stopped short of recommending respirators for groups not deemed "at increased risk of severe illness from influenza", except for occupational use in healthcare.[78] NIOSH also emphasized the differences in fit between an N95 respirator and a surgical mask for prevention against the flu.[79]

For those in the general public wishing to wear N95 respirators, properly wearing a N95 was noted to be difficult, but the tendency for people to distance themselves from those wearing masks was said to compliment the six-foot social distancing rules at the time.[80]

H1N1 respirator/mask randomized control trials

[edit]

Around the time of the H1N1 pandemic, randomized control trial studies of masks started being done, comparing surgical masks and N95 respirators with the tendency for medical staff to be infected by the flu. One paper concluded that N95s were better than surgical masks, but its results were later called into question.[81] Another paper claimed that protection provided by an N95 respirator compared similarly to a surgical mask, but the study did not control health care personnel potentially being exposed outside, without respirators, via the community.[82][b]

After the 2009 H1N1 flu season, the CDC issued guidelines recommending surgical masks instead, after complaints were leveled by various groups on the effectiveness of surgical masks compared to N95 respirators, along with complaints about comfort. The new recommendations were met with approval by groups like the Society for Healthcare Epidemiology of America.[84][85]

COVID-19 pandemic

[edit]
See also: COVID-19 pandemic
Lab worker with mask in 2020
A Hospital Corpsman wearing a Surgical N95 during the initial months of the COVID-19 pandemic

During the COVID-19 pandemic, the mask and respirator market rapidly grew, along with counterfeit respirators.[86] NIOSH, on behalf of the Department of Health and Human Services, filed a trademark application on June 17, 2020, for various 42 CFR 84 trademarks, including the N95, allowing NIOSH to enforce rules on counterfeit masks outside of rules defined in 42 CFR 84.[87][9] The trademarks were registered in 2022.[88]

Global shortages during the COVID-19 pandemic

[edit]
Main article: Face masks during the COVID-19 pandemic § N95 and FFP masks

The Strategic National Stockpile had not been refilled following the H1N1 pandemic,[89] and by April 2020, Department of Homeland Security officials reported that the supply of respirators and other PPE in the stockpile was nearly gone.[90] Respirators came to be in short supply and high demand during the COVID-19 pandemic, causing price gouging and hoarding, often leading to confiscation of masks.[91][92][93] Production of N95 respirators was limited due to constraints on the supply of nonwoven polypropylene fabric as well as the cessation of exports from China.[1][94]

Also in early April 2020, the United States federal government, invoking the DPA, ordered 3M to stop exporting N95 respirators to customers in Canada and Latin America, and to keep them within the U.S. instead. However, 3M refused, saying: "Ceasing all export of respirators produced in the United States would likely cause other countries to retaliate and do the same, as some have already done. If that were to occur, the net number of respirators being made available to the United States would actually decrease. That is the opposite of what we and the administration, on behalf of the American people, both seek."[95]

Dropping of mask mandates in hospitals

[edit]
These paragraphs are an excerpt from Source control (respiratory disease) § Post-2023.[edit]

By 2023, The New York Times noted that the CDC had dropped mandates for masks in hospitals during COVID, limiting the COVID policies to an advisory role. Use of masks for source control is still recommended in times of high viral activity, but the CDC did not provide numbers for benchmarks. The new policies are thought, according to the New York Times, based on various citations to medical literature, to increase mortality among vulnerable patients, especially those with cancer.[96]

The New York Times article cites a paper published in 2023, that suggests the high mortality of cancer patients following the Omicron wave may have been due to relaxing of policies preventing COVID-19 transmission[97] (like source control policies). The 2023 paper also cites a research letter published in 2022, that suggests that the surge of COVID-19 cases in hospitals may have been due to the high contagiousness of Omicron,[98] an article which suggested a high secondary attack rate relative to Delta,[99] and papers finding increased mortality of cancer patients due to higher rates of breakthrough infections.[100][101]

Also in 2023, new draft guidelines were proposed by the CDC HICPAC, to update the pre-COVID 2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings.[c] The proposed updates were met with disapproval by the National Nurses United union, as they felt the changes did not go far enough.[96] Changes included clarifying by adding "source control" as a qualification for the use of "barrier precautions".[102]

Criticism of N95 RCTs and other controversial studies

[edit]

Following previous H1N1 randomized control trials comparing N95s and surgical masks, new RCTs were published. Major flaws were noted, including contraction of virus outside hospital, the lack of controls over time in hospital, and assumptions made about transmission via droplets instead of aerosols.[103]

In addition, in 2024, a paper published in the American Society for Microbiology Clinical Microbiology Reviews stated there were harms in continued undue weight being placed on RCTs and flawed mask studies in a social and political context, as retracted papers continue to be circulated to justify certain masking behaviors and beliefs. One retracted JAMA paper[104] garnered a million views, while another retracted paper in Frontiers Public Health[105] continues to circulate across social media.[106]

H5N1 outbreak

[edit]
See also: 2020–2024 H5N1 outbreak § United States

Among dairy workers

[edit]

The CDC recommends farm workers wear PPE, including N95 or better respirators, when working with farm animals potentially infected with H5N1.[107][108] However, outbreaks of H5N1 have continued among dairy workers, likely due to workers' fear of retaliation by their employers, and reluctance by employers and state officials to allow CDC investigators into dairy farms.[109]

Selected patents

[edit]
An image of two N95 Kimberly-Clark duckbill respirators.
The patent to this 'Duckbill' style respirator was assigned to Kimberly-Clark in the US until expiry in 2015.
  • US patent 3333585, Robert J Barghini, Walter M Westberg, Patrick H Carey Jr, "Cold weather face mask", published 1967-08-01, issued 1967-08-01, assigned to 3M Co 
  • US patent 3971373A, David L. Braun, "Particle-loaded microfiber sheet product and respirators made therefrom", published 1976-07-27, issued 1976-07-27, assigned to 3M Co 
  • US patent 4215682A, Donald A. Kubik & Charles I. Davis, "Melt-blown fibrous electrets", published 1980-08-05, issued 1980-08-05, assigned to 3M Co 
  • US patent 4536440A, Harvey J. Berg, "Molded fibrous filtration products", published 1985-08-20, issued 1985-08-20, assigned to 3M Co 
  • US patent 4807619, James F. Dyrud, Harvey J. Berg, Alice C. Murray, "Resilient shape-retaining fibrous filtration face mask", published 1989-02-28, issued 1989-02-28, assigned to 3M Co 
  • US patent 4850347, Martin R. Skov, "Face mask", published 1989-07-25, issued 1989-07-25, assigned to Moldex Metric Inc 
  • US patent 4856509, Jerome H. Lemelson, "Face mask and method", published 1989-08-15, issued 1989-08-15 
  • US patent 5307796A, Joseph P. Kronzer, Roger J. Stumo, James F. Dyrud, Harvey J. Berg, "Methods of forming fibrous filtration face masks", published 1994-05-03, issued 1994-05-03, assigned to 3M Co 
  • US patent 3985132A, Elvin L. Boyce & William Keith Robinson, "Filter mask", published 1976-10-12, issued 1976-10-12, assigned to Kimberly-Clark Worldwide Inc. and Alpha Pro Tech Inc.  Marketed by AlphaProTech as 'Magic Arch.'
  • US patent 4688566A, Elvin L. Boyce, "Filter mask", published 1987-04-25, issued 1987-04-25, assigned to Alpha Pro Tech Inc. 

'Duckbill' style

[edit]
  • US patent 5322061A, Kevin K. Brunson, "Disposable Aerosol Mask", published 1994-06-21, issued 1998-06-02, assigned to Kimberly-Clark Worldwide Inc. 
  • US patent 5694925A, "Face mask with enhanced seal and method", published 1997-12-09, issued 1997-12-09, assigned to Kimberly-Clark Worldwide Inc. 

See also

[edit]

Notes

[edit]
  1. ^ a b c This refers to the MSHA's definition of 'HEPA' under 30 CFR Part 11 for respirators, which is 99.97% filtration of 0.3 micron DOP, not the EN 1822 or ISO 29463 definition of HEPA.
  2. ^ A later preprint study by the same lead author (Loeb) claiming the same thing was found to be fraudulent in multiple ways, including use of unregistered study sites, repeated alteration of mathematical analysis methods to obscure the evidence in the data, as well as concealment of conflicts of interest; the actual data in that study showed that N95s were superior.[83]
  3. ^ See Source control (respiratory disease)#Pre-COVID

References

[edit]
  1. ^ a b Xie, John (March 19, 2020). "World Depends on China for Face Masks But Can Country Deliver?". Voice of America.
  2. ^ Feng, Emily (March 16, 2020). "COVID-19 Has Caused A Shortage Of Face Masks. But They're Surprisingly Hard To Make". Goats and Soda. NPR.
  3. ^ Barrett, Leonard W.; Rousseau, Alan D. (1998). "Aerosol Loading Performance of Electret Filter Media". American Industrial Hygiene Association Journal. 59 (8): 532–539. doi:10.1080/15428119891010703.
  4. ^ a b c d NIOSH Guide to the Selection and Use of Particulate Respirators Certified Under 42 CFR 84. 1996.
  5. ^ "NIOSH-Approved N95 Particulate Filtering Facepiece Respirators - A Suppliers List". U.S. National Institute for Occupational Safety and Health. March 19, 2020. Retrieved March 27, 2020.
  6. ^ "Respirator Trusted-Source: Selection FAQs". U.S. National Institute for Occupational Safety and Health. March 12, 2020. Retrieved March 28, 2020.
  7. ^ "Certified Equipment List | NPPTL | NIOSH | CDC". www.cdc.gov. June 4, 2020.
  8. ^ "Respirator Trusted-Source Information | NPPTL | NIOSH | CDC". www.cdc.gov. August 3, 2020.
  9. ^ a b "Counterfeit Respirators / Misrepresentation of NIOSH-Approval". NIOSH, Centers of Disease Control and Prevention. Retrieved October 27, 2020.
  10. ^ "Comparison of FFP2, KN95, and N95 and Other Filtering Facepiece Respirator Classes" (PDF). 3M Technical Data Bulletin. January 1, 2020. Retrieved March 28, 2020.
  11. ^ "Health Canada issues recall of some KN95 masks made in China". Canadian Broadcasting Corporation. Retrieved October 25, 2020.
  12. ^ "Certain Filtering Facepiece Respirators from China May Not Provide Adequate Respiratory Protection - Letter to Health Care Providers". U.S. Food and Drug Administration. Retrieved October 25, 2020.
  13. ^ "Important safety information for certain respirator masks". Health Canada. Retrieved October 25, 2020.
  14. ^ "Transcript for the OSHA Training Video Entitled Counterfeit & Altered Respirators: The Importance of Checking for NIOSH Certification". US Department of Labor, OSHA. January 2012. Archived from the original on June 3, 2024. Retrieved June 3, 2024.
  15. ^ "Counterfeit Respirators / Misrepresentation of NIOSH Approval". May 23, 2024.
  16. ^ Howard W., Spencer. "The Historic and Cultural Importance of the HAWKS NEST TUNNEL DISASTER" (PDF). American Society of Safety Professionals.
  17. ^ a b Spelce, David; Rehak, Timothy R; Meltzer, Richard W; Johnson, James S (2019). "History of U.S. Respirator Approval (Continued) Particulate Respirators". J Int Soc Respir Prot. 36 (2): 37–55. PMC 7307331. PMID 32572305.
  18. ^ "Federal Coal Mine and Safety Act of 1969". US Department of Labor, US Mine Safety and Health Administration.
  19. ^ US EPA, OP (February 22, 2013). "Summary of the Occupational Safety and Health Act". www.epa.gov. Retrieved August 28, 2021.
  20. ^ "38 FR 11458" (PDF). May 8, 1973.
  21. ^ "ANSI Z88.2: American National Standard for Respiratory Protection" (PDF). August 6, 1992.
  22. ^ a b c d "DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service 42 CFR Part 84" (PDF). US Federal Register. pp. 26850-26893. Retrieved May 8, 2024.
  23. ^ Moran, John B. (1988). "Personal Protective Equipment". Applied Industrial Hygiene. 3 (5). doi:10.1080/08828032.1988.10388554.
  24. ^ Federal Register (PDF), vol. 52, August 27, 1987, p. 32402
  25. ^ "DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Guidelines for Preventing the Transmission of Mycobacterium Tuberculosis in Health-Care Facilities, 1994" (PDF). US Federal Register. Retrieved May 8, 2024.
  26. ^ "TB Respiratory Protection Program In Health Care Facilities Administrator's Guide" (PDF). U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health. September 1999. doi:10.26616/NIOSHPUB99143.
  27. ^ "DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service 42 CFR Part 84 RIN 0905–AB58 Respiratory Protective Devices" (PDF). US Federal Register. June 8, 1995. Retrieved April 27, 2024.
  28. ^ "42 CFR 84 Respiratory Protective Devices". NIOSH. August 25, 1995. Archived from the original on December 30, 1996.
  29. ^ Note: the following source cites July 1, 1998 as the end date for the transition period, contradicting official NIOSH publications. Herring Jr., Ronald N. (1997). "42 CFR Part 84: It's time to change respirators... but how?". Engineer's Digest. pp. 14–23.
  30. ^ "CHANGES IN OCCUPATIONAL SAFETY REGS WILL PERMIT BETTER RESPIRATORS TO PROTECT AGAINST DUST AND DISEASE". NIOSH. June 2, 1995. Archived from the original on December 31, 1996.
  31. ^ a b c d D'Alessandro, Maryann M.; Cichowicz, Jaclyn Krah (March 16, 2020). "Proper N95 Respirator Use for Respiratory Protection Preparedness". NIOSH Science Blog. Retrieved March 27, 2020. Public Domain This article incorporates text from this source, which is in the public domain.
  32. ^ "Medical Evaluations for Workers Who Use Respirators". U.S. Occupational Safety and Health Administration. Retrieved January 30, 2024.
  33. ^ "Ancillary Respirator Information". U.S. National Institute for Occupational Safety and Health. January 26, 2018. Retrieved February 12, 2020.
  34. ^ Hui, David S.; Chow, Benny K.; Chu, Leo; Ng, Susanna S.; Lee, Nelson; Gin, Tony; Chan, Matthew T. V. (December 5, 2012). "Exhaled Air Dispersion during Coughing with and without Wearing a Surgical or N95 Mask". PLOS ONE. 7 (12): e50845. Bibcode:2012PLoSO...750845H. doi:10.1371/journal.pone.0050845. ISSN 1932-6203. PMC 3516468. PMID 23239991.
  35. ^ Bach, Michael (July 6, 2017). "Understanding respiratory protection options in healthcare: the overlooked elastomeric". NIOSH Science Blog. Retrieved April 21, 2020.
  36. ^ Garvey, Donald J. (April 1, 2010). "Constructing a Powered Air Purifying Respirator System". EHS Today. Retrieved April 21, 2020.
  37. ^ a b "N95 Respirators, Surgical Masks, Face Masks, and Barrier Face Coverings". US Food and Drug Administration. March 10, 2023. Retrieved April 27, 2024.
  38. ^ Hull, Matthew S. (March 2016). "Building a Safety Program to Protect the Nanotechnology Workforce: A Guide for Small to Medium-Sized Enterprises". U.S. National Institute for Occupational Safety and Health. doi:10.26616/NIOSHPUB2016102. hdl:10919/76615. Retrieved March 5, 2017.
  39. ^ "Respiratory Protection for Workers Handling Engineered Nanoparticles". NIOSH Science Blog. U.S. National Institute for Occupational Safety and Health. December 7, 2011. Retrieved March 15, 2017.
  40. ^ "Multi-Walled Carbon Nanotubes; Significant New Use Rule (40 CFR 721.10155)". Federal Register, Volume 76 Issue 88. U.S. Environmental Protection Agency via U.S. Government Publishing Office. May 6, 2011. Retrieved March 15, 2017.
  41. ^ "Dust Masks, What's in a Rating | N95, P95, N100 etc". www.envirosafetyproducts.com. Retrieved April 12, 2021.
  42. ^ a b Bollinger, Nancy (October 1, 2004). "NIOSH respirator selection logic". U.S. National Institute for Occupational Safety and Health: 5–9. doi:10.26616/NIOSHPUB2005100.
  43. ^ "Respirator Reuse FAQs". U.S. National Institute for Occupational Safety and Health. January 30, 2018. Retrieved April 20, 2020.
  44. ^ a b Portnoff, L; Schall, J; Brannen, J; Suhon, N; Strickland, K; Meyers, J (December 1, 2020). "Filtering Facepiece Respirators with an Exhalation Valve: Measurements of Filtration Efficiency to Evaluate Their Potential for Source Control". NIOSH (Publication No. 2021-107). U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health. doi:10.26616/nioshpub2021107.
  45. ^ "A Comparison of Surgical Masks, Surgical N95 Respirators, and Industrial N95 Respirators". Occupational Health & Safety. May 1, 2014. Retrieved April 7, 2020.
  46. ^ "Respirator Trusted-Source Information: Ancillary Respirator Information". U.S. National Institute for Occupational Safety and Health. January 26, 2018. Retrieved February 12, 2020.
  47. ^ "Surgical N95 vs. Standard N95 – Which to Consider?" (PDF). 3M Company. March 2020. Retrieved June 12, 2022.
  48. ^ 2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings (PDF). U.S. Centers for Disease Control and Prevention. July 2019. pp. 55–56. Retrieved February 9, 2020.
  49. ^ a b c d e "Strategies for Optimizing the Supply of N95 Respirators: Crisis/Alternate Strategies". U.S. Centers for Disease Control and Prevention. March 17, 2020. Retrieved March 28, 2020. Public Domain This article incorporates text from this source, which is in the public domain.
  50. ^ "Release of Stockpiled N95 Filtering Facepiece Respirators Beyond the Manufacturer-Designated Shelf Life: Considerations for the COVID-19 Response". U.S. Centers for Disease Control and Prevention. February 28, 2020. Retrieved March 28, 2020.
  51. ^ a b "Recommended Guidance for Extended Use and Limited Reuse of N95 Filtering Facepiece Respirators in Healthcare Settings". U.S. National Institute for Occupational Safety and Health. March 27, 2020. Retrieved March 28, 2020.
  52. ^ "Rational use of personal protective equipment for coronavirus disease 2019 (COVID-19)" (PDF). World Health Organization. February 27, 2020. Retrieved March 21, 2020.
  53. ^ a b "Decontamination and Reuse of Filtering Facepiece Respirators". U.S. Centers for Disease Control and Prevention. April 9, 2020. Retrieved April 20, 2020. Public Domain This article incorporates text from this source, which is in the public domain.
  54. ^ Srinivasan S, Peh W (2020). "N95 Filtering Facepiece Respirators during the COVID-19 Pandemic: Basics, Types, and Shortage Solutions". Malaysian Orthopedic Journal. 14 (2): 16–22. doi:10.5704/MOJ.2007.002. PMC 7513643. PMID 32983373.
  55. ^ Viscusi, Dennis J.; Bergman, Michael S.; Eimer, Benjamin C.; Shaffer, Ronald E. (November 2009). "Evaluation of Five Decontamination Methods for Filtering Facepiece Respirators". Annals of Occupational Hygiene. 53 (8): 815–827. doi:10.1093/annhyg/mep070. ISSN 0003-4878. PMC 2781738. PMID 19805391.
  56. ^ a b "Addressing COVID-19 Face Mask Shortages". Stanford University School of Medicine. March 25, 2020. Retrieved March 27, 2020.
  57. ^ March 2020, Rafi Letzter – Staff Writer (March 24, 2020). "Doctors scramble for best practices on reusing medical masks during shortage". livescience.com. Retrieved March 27, 2020.{{cite web}}: CS1 maint: numeric names: authors list (link)
  58. ^ Schwartz, Antony; Stiegel, Matthew; Greeson, Nicole; et al. "Decontamination and Reuse of N95 Respirators with Hydrogen Peroxide Vapor to Address Worldwide Personal Protective Equipment Shortages During the SARS-CoV-2 (COVID-19) Pandemic" (PDF). Duke University. Archived from the original (PDF) on March 27, 2020. Retrieved March 28, 2020.
  59. ^ Andrew, Scottie (March 27, 2020). "Duke researchers are decontaminating N95 masks so doctors can reuse them to treat coronavirus patients". CNN.
  60. ^ Billman, Jeffrey C. (March 26, 2020). "Duke Researchers Find Way to Decontaminate and Reuse N95 Masks, Possibly Alleviating Critical Shortfall". INDY Week. Archived from the original on July 19, 2020. Retrieved March 27, 2020.
  61. ^ Schladen, Marty (March 29, 2020). "FDA lifts restrictions on Ohio-based Battelle's mask-sterilizing technology amid coronavirus shortages". USA Today. Retrieved March 30, 2020.
  62. ^ a b "N95 Respirators and Surgical Masks (Face Masks)". U.S. Food and Drug Administration. March 11, 2020. Retrieved March 28, 2020. Public Domain This article incorporates text from this source, which is in the public domain.
  63. ^ Brosseau, Lisa; Ann, Roland Berry (October 14, 2009). "N95 Respirators and Surgical Masks". NIOSH Science Blog. Retrieved March 28, 2020. Public Domain This article incorporates text from this source, which is in the public domain.
  64. ^ Andrejko, Kristin L.; et al. (2022). "Effectiveness of Face Mask or Respirator Use in Indoor Public Settings for Prevention of SARS-CoV-2 Infection — California, February–December 2021". MMWR. Morbidity and Mortality Weekly Report. 71 (6): 212–216. doi:10.15585/mmwr.mm7106e1. PMC 8830622. PMID 35143470. Retrieved January 30, 2024.
  65. ^ a b c "DEPARTMENT OF LABOR Occupational Safety and Health Administration 29 CFR Part 1910 [Docket No. H-371] RIN 1218-AB46 Occupational Exposure to Tuberculosis".
  66. ^ Pugliese, Gina (1994). "OSHA Announces Plans for a TB Standard". Infection Control & Hospital Epidemiology. 15 (4): 277. doi:10.1086/646909.
  67. ^ "Introduction". Introduction. Tuberculosis in the Workplace. National Academies Press (US). 2001.
  68. ^ "Part III DEPARTMENT OF LABOR Occupational Safety and Health Administration 29 CFR Part 1910 [Docket No. H-371] RIN 1218-AB46 Occupational Exposure to Tuberculosis".
  69. ^ Coen, Jon (April 7, 2003). "Do Surgical Masks Stop SARS?". Slate.
  70. ^ "Update: Severe Acute Respiratory Syndrome --- United States, 2003". CDC MMWR Weekly. April 25, 2003.
  71. ^ Roos, Robert (October 8, 2003). "National stockpile of SARS safety gear proposed". University of Minnesota CIDRAP News.
  72. ^ "Re. SARS Advisory" (PDF). February 10, 2004.
  73. ^ "SARS Commission Final Report: Volume Three" (PDF).
  74. ^ Svoboda, Tomislav; Henry, Bonnie; Shulman, Leslie; Kennedy, Erin; Rea, Elizabeth; Ng, Wil; Wallington, Tamara; Yaffe, Barbara; Gournis, Effie; Vicencio, Elisa; Basrur, Sheela; Glazier, Richard H. (2004). "Public Health Measures to Control the Spread of the Severe Acute Respiratory Syndrome during the Outbreak in Toronto". New England Journal of Medicine. 350 (23): 2352–2361. doi:10.1056/NEJMoa032111. PMID 15175437.
  75. ^ a b c "2007 Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings" (PDF).
  76. ^ a b "Hospital Respiratory Protection Program Toolkit" (PDF). OSHA. May 2015. Archived from the original (PDF) on April 28, 2018.
  77. ^ "N95-authorization.PDF" (PDF). DHHS. May 1, 2009. Retrieved June 17, 2024.
  78. ^ "Interim Recommendations for Facemask and Respirator Use to Reduce Novel Influenza A (H1N1) Virus Transmission". CDC. May 8, 2009. Archived from the original on September 1, 2009.
  79. ^ Brosseau, Lisa; Ann, Roland Berry (October 14, 2009). "N95 Respirators and Surgical Masks".
  80. ^ Allison, Aubrey (May 4, 2009). "Do Face Masks Protect From Flu?". NPR.
  81. ^ Pallarito, Karen (November 6, 2009). "Respirator or face mask? Best H1N1 protection still debated". Health.com.
  82. ^ Loeb, Mark; Dafoe, Nancy; Mahony, James; John, Michael; Sarabia, Alicia; Glavin, Verne; Webby, Richard; Smieja, Marek; Earn, David J. D.; Chong, Sylvia; Webb, Ashley; Walter, Stephen D. (2009). "Surgical Mask vs N95 Respirator for Preventing Influenza Among Health Care Workers". JAMA. 302 (17): 1865–1871. doi:10.1001/jama.2009.1466. PMID 19797474.
  83. ^ Ungrin, Mark. ""Medical masks versus N95 respirators for preventing COVID-19 among health care workers: A secondary analysis of findings inconsistent with prior understanding reflects the expected inferiority of medical masks"".
  84. ^ Schnirring, Lisa (September 20, 2010). "CDC finalizes flu prevention guidance for health settings". University of Minnesota CIDRAP News.
  85. ^ The Society for Healthcare Epidemiology of America's letter to President Obama: "SHEA-IDSA-APIC Letter on Federal PPE Guidance" (PDF). The Society for Healthcare Epidemiology of America. November 5, 2009. Archived from the original (PDF) on December 8, 2024.
  86. ^ Joskow, Paul L. (February 27, 2022). "From Scarcity to Abundance: Complementary Government and Private Initiatives to Manage the Allocation of N95 Masks in the U.S. During the COVID-19 Pandemic" (PDF).
  87. ^ "Trademark Status & Document Retrieval". 90006709.
  88. ^ "NIOSH Registers Respirator Certification Marks with Patent and Trademark Office". American Industrial Hygiene Association. January 20, 2022.
  89. ^ Taddonio, Patrice (October 6, 2020). "Depleted National Stockpile Contributed to COVID PPE Shortage: 'You Can't Be Prepared If You're Not Funded to Be Prepared'". PBS Frontline.
  90. ^ Miroff, Nick (April 2, 2020). "Protective gear in national stockpile is nearly depleted, DHS officials say". The Washington Post.
  91. ^ Johnson, Martin (March 26, 2020). "Feds have 1.5 million expired N95 masks in storage despite CDC clearing them for use on COVID-19: report". The Hill.
  92. ^ Nicas, Jack (April 3, 2020). "It's Bedlam in the Mask Market, as Profiteers Out-Hustle Good Samaritans". The New York Times. ISSN 0362-4331. Retrieved April 16, 2020.
  93. ^ "3 million masks ordered by Massachusetts were confiscated in Port of New York, leading to creative alternative". WCVB. Hearst Television. April 3, 2020. Retrieved April 16, 2020.
  94. ^ Evan, Melanie; Hufford, Austen (March 7, 2020). "Critical Component of Protective Masks in Short Supply". The Wall Street Journal.
  95. ^ Evans, Pete (2020). "3M faces pressure from Trump order to stop exporting N95 masks to Canada". CBC. Retrieved October 26, 2020.
  96. ^ a b Mandavilli A (September 23, 2023). "In Hospitals, Viruses Are Everywhere. Masks Are Not". New York Times. Retrieved June 27, 2024.
  97. ^ Potter AL, Vaddaraju V, Venkateswaran S, Mansur A, Bajaj SS, Kiang MV, Jena AB, Yang CJ (October 2023). "Deaths Due to COVID-19 in Patients With Cancer During Different Waves of the Pandemic in the US". JAMA Oncology. 9 (10): 1417–1422. doi:10.1001/jamaoncol.2023.3066. PMID 37651113.
  98. ^ Klompas M, Pandolfi MC, Nisar AB, Baker MA, Rhee C (July 2022). "Association of Omicron vs Wild-type SARS-CoV-2 Variants With Hospital-Onset SARS-CoV-2 Infections in a US Regional Hospital System". Jama. 328 (3): 296–298. doi:10.1001/jama.2022.9609. PMC 9201738. PMID 35704347.
  99. ^ Lyngse FP, Mortensen LH, Denwood MJ, Christiansen LE, Møller CH, Skov RL, Spiess K, Fomsgaard A, Lassaunière R, Rasmussen M, Stegger M, Nielsen C, Sieber RN, Cohen AS, Møller FT, Overvad M, Mølbak K, Krause TG, Kirkeby CT (September 2022). "Household transmission of the SARS-CoV-2 Omicron variant in Denmark". Nature Communications. 13 (1): 5573. Bibcode:2022NatCo..13.5573L. doi:10.1038/s41467-022-33328-3. PMID 36151099.
  100. ^ Gong IY, Vijenthira A, Powis M, Calzavara A, Patrikar A, Sutradhar R, Hicks LK, Wilton D, Singh S, Krzyzanowska MK, Cheung MC (March 2023). "Association of COVID-19 Vaccination With Breakthrough Infections and Complications in Patients With Cancer". JAMA Oncology. 9 (3): 386–394. doi:10.1001/jamaoncol.2022.6815. PMC 10020872. PMID 36580318.
  101. ^ Potter AL, Vaddaraju V, Venkateswaran S, Mansur A, Bajaj SS, Kiang MV, Jena AB, Yang CJ (October 2023). "Deaths Due to COVID-19 in Patients With Cancer During Different Waves of the Pandemic in the US". JAMA Oncology. 9 (10): 1417–1422. doi:10.1001/jamaoncol.2023.3066. PMID 37651113.
  102. ^ "Proposed Update to Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings (2007), 'Protective Environment' Recommendation" (PDF). Archived from the original (PDF) on August 22, 2023.
  103. ^ "Study on masks vs N95 respirators for health workers spurs concerns". University of Minnesota CIDRAP News. November 29, 2022.
  104. ^ Christakis, Dimitri; Fontanarosa, Phil B. (2021). "Notice of Retraction. Walach H, et al. Experimental Assessment of Carbon Dioxide Content in Inhaled Air with or Without Face Masks in Healthy Children: A Randomized Clinical Trial. JAMA Pediatr. Published online June 30, 2021". JAMA Pediatrics. 175 (9): e213252. doi:10.1001/jamapediatrics.2021.3252. PMID 34269801.
  105. ^ Frontiers Editorial Office (2023). "Retraction: Physio-metabolic and clinical consequences of wearing face masks—Systematic review with meta-analysis and comprehensive evaluation". Frontiers in Public Health. 11. doi:10.3389/fpubh.2023.1221666. PMC 10251234. PMID 37304106.
  106. ^ Greenhalgh, Trisha; MacIntyre, C. Raina; Baker, Michael G.; Bhattacharjee, Shovon; Chughtai, Abrar A.; Fisman, David; Kunasekaran, Mohana; Kvalsvig, Amanda; Lupton, Deborah; Oliver, Matt; Tawfiq, Essa; Ungrin, Mark; Vipond, Joe (2024). "Masks and respirators for prevention of respiratory infections: A state of the science review". Clinical Microbiology Reviews. 37 (2): e0012423. doi:10.1128/cmr.00124-23. hdl:1959.4/102268. PMC 11326136. PMID 38775460.
  107. ^ "Key Public Health Prevention Recommendations for HPAI A(H5N1)". United States CDC. June 10, 2024. Retrieved June 15, 2024.
  108. ^ "Protect Yourself From H5N1 When Working With Farm Animals" (PDF). United States CDC. Retrieved June 15, 2024.
  109. ^ Nix, Jessica; Griffin, Riley; Gale, Jason (May 8, 2024). "Just One Human Is Infected by Bird Flu in the US. More Cases Are Likely". Bloomberg.

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