The 2005–06 season is River Plate's 76nd season in the Argentine Primera División.
The season was split into two tournaments (format adopted since 1990–91 season) Apertura (Opening) 2005 (from August to December 2005), and Clausura (Closing) 2006 (from February to June 2006).
The club's kit was provided by Adidas, and the sponsor was Budweiser beer.
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.
Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply. Players may hold more than one non-FIFA nationality.