IL7RA
外觀
白介素-7受體α亞基(Interleukin-7 receptor subunit alpha,縮寫IL7R-α或IL7RA)也稱為分化簇127(CD127,cluster of differentiation 127)是一種細胞表面蛋白質,由人類基因 IL7R 編碼[6],與γ鏈(CD132)共同組成白介素-7受體(IL7R,一種I型細胞因子受體),能結合白血球介素-7(IL7)與胸腺基質淋巴細胞生成素(TSLP)[7]。
參考資料
[編輯]- ^ 與IL7R相關的疾病;在維基數據上查看/編輯參考.
- ^ 2.0 2.1 2.2 GRCh38: Ensembl release 89: ENSG00000168685 - Ensembl, May 2017
- ^ 3.0 3.1 3.2 GRCm38: Ensembl release 89: ENSMUSG00000003882 - Ensembl, May 2017
- ^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Entrez Gene: IL7R interleukin 7 receptor.
- ^ Goodwin RG, Friend D, Ziegler SF, Jerzy R, Falk BA, Gimpel S, Cosman D, Dower SK, March CJ, Namen AE. Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily. Cell. March 1990, 60 (6): 941–51. PMID 2317865. S2CID 45181020. doi:10.1016/0092-8674(90)90342-C.
外部連結
[編輯]- 醫學主題詞表(MeSH):IL7R+protein,+human
- PDB中UniProt可用的所有結構資訊之概述:P16871 (Human Interleukin-7 receptor subunit alpha) 在PDBe-KB。
- PDB中UniProt可用的所有結構資訊之概述:P16872 (Mouse Interleukin-7 receptor subunit alpha) 在PDBe-KB。